Purported Mechanisms of Action and Potential Therapeutic Benefits of EBOO Therapy:EBOO therapy is purported to exert its therapeutic effects through several mechanisms, leading to a variety of potential health benefits. One of the primary goals of EBOO is to enhance the oxygenation of the blood.3 By increasing the blood's capacity to carry oxygen, EBOO aims to improve the delivery of oxygen to tissues throughout the body, which can be particularly advantageous in conditions where tissue oxygen supply is compromised.3 Furthermore, proponents suggest that EBOO may play a role in modulating the immune system.3 It is believed that the introduction of ozone into the bloodstream can stimulate an enhanced immune response, potentially aiding the body in its defense against infections and various illnesses.3 Another key aspect of EBOO therapy is its potential to support detoxification processes.3 The ozone component is thought to facilitate the breakdown of toxins and metabolic waste products, while the filtration component in some EBOO systems is designed to physically remove impurities, heavy metals, and cellular debris from the blood.5 Additionally, ozone therapy, including EBOO, is known for its anti-inflammatory properties.1 This reduction in inflammation can contribute to alleviating pain and improving muscle mobility.1 Ozone also exhibits antimicrobial effects, with the ability to inactivate bacteria, viruses, fungi, yeast, and protozoa.4 Consequently, EBOO therapy is being explored as a supportive treatment for various chronic conditions, including chronic fatigue syndrome, autoimmune disorders, and Lyme disease.3 The ozonated blood in EBOO has an increased oxygen content, which can lead to improved blood circulation and more efficient delivery of essential nutrients to the body's tissues.5 This improved blood flow and cellular oxygen utilization are thought to contribute to overall well-being and an enhanced quality of life.7 Furthermore, the introduction of ozone is believed to stimulate antioxidant enzymes, which play a crucial role in protecting cells from oxidative damage.3 Some proponents also suggest that EBOO can facilitate the release of growth factors, potentially aiding in the regeneration of damaged joints and deteriorated discs.7 In the context of autoimmune diseases, EBOO is proposed to modulate the immune system, potentially reducing the severity of autoimmune flare-ups.8 The delivery of ozone to the bloodstream in EBOO is also thought to neutralize free radicals, thereby reducing oxidative stress, a key driver of inflammation.7 The multifaceted nature of these purported benefits suggests that EBOO therapy is being investigated for a wide spectrum of health challenges, likely due to its potential to influence various physiological systems.